Articles with the keyword: 


Drug giants unite to develop cancer therapy
sea-maid submitted, created time 9 months 2 weeks (www.nature.com)
An unusual collaboration between two pharmaceutical giants could herald a welcome change in how cancer therapies are developed, cancer researchers say. 


Drug Combo Keeps Kidney Artery-Vein Grafts Viable
sea-maid submitted, created time 9 months 3 weeks (healthlibrary.epnet.com)
A combination of aspirin and the anti-clotting drug dipyridamole reduces blockages and extends the useful life of new artery-vein access grafts used for kidney dialysis, new research has found. 
Firefly Genes In Mice Allow Testing Of New Therapy Against Lymphoma
Eric wu submitted, created time 2 years 2 months (www.sciencedaily.com)
Researchers here have figured out a way to use a firefly gene to let them see just how effective a new drug combination actually is against some forms of cancer and its serious complication. 


Scientists unveil structure of molecular target of many drugs
jimmy submitted, created time 2 years 4 months (www.nigms.nih.gov)
Scientists have captured the first detailed, three-dimensional look at the beta2-adrenergic receptor -- a human G protein-coupled receptor belonging to a family of membrane proteins targeted by about half of today's pharmaceuticals. 


New drug makes weight loss safer
jackson submitted, created time 2 years 5 months (www.eurekalert.org)
Dr. Nir Barak of TAU has adapted a well-known drug used to treat vertigo for a new purpose: to treat obesity without dangerous side effects. 


Plants can be used to study how and why people respond differently to drugs
carly submitted, created time 2 years 5 months (www.eurekalert.org)
While prescription medications work successfully to cure an ailment in some people, in others the same dose of the same drug can cause an adverse reaction or no response at all. According to a research team led by UC Riverside's Sean Cutler, such variation in drug responses can be analyzed by studying much simpler organisms -- like plants. 


Women prescribed drugs linked to birth defects not often advised to use birth control
richard submitted, created time 2 years 6 months (www.eurekalert.org)
Although prescription medications that may increase the risk of birth defects are commonly used by women in their childbearing years, only about half receive contraceptive counseling from their health-care providers, according to a large-scale study from the University of Pittsburgh School of Medicine. The study found that one in six women of reproductive age filled a prescription for a medication labeled by the FDA as increasing the risk of fetal abnormalities. 


Melanoma drug revs immune cells but cancer cells ignore it
benjiamin submitted, created time 2 years 6 months (researchnews.osu.edu)
A new study shows that an important drug used in the treatment of malignant melanoma has little effect on the melanoma cells themselves. Instead, it activates immune-system cells to fight the disease. The drug, called interferon alpha, is used to clean up microscopic tumor cells that may remain in the body following surgery for the disease. It is the only drug approved for this purpose. 


Advantages of ADHD drugs may disappear over time
abc01 submitted, created time 2 years 7 months (www.reutershealth.com)
The results of a study of 579 children with ADHD, conducted by the National Institutes of Mental Health, have indicated that medication usage, alone or in combination with behavioral therapy, provides better patient outcomes than just behavioral therapy or routine community care after 14 and 24 months. 


Drug protects brain cells in Huntington's disease model, researchers find
bianjie submitted, created time 2 years 7 months (www.eurekalert.org)
A drug used in some countries to treat the symptoms of Huntington's disease prevents death of brain cells in mice genetically engineered to mimic the hereditary condition, UT Southwestern Medical Center researchers have found. 


Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
bianjie submitted, created time 2 years 7 months (www.pnas.org)
Arsenic trioxide (ATO) is an effective cancer therapeutic drug for acute promyelocytic leukemia and has potential anticancer activity against a wide range of solid tumors. ATO exerts its effect mainly through elevated oxidative stress, but the exact molecular mechanism remains elusive. 


Would You Like Fries With That? Value Meal Could Lower Drug Costs
bianjie submitted, created time 2 years 8 months (www.sciencedaily.com)
Exploiting interactions between food and drugs could dramatically lower the rapidly rising costs of several anticancer drugs, and perhaps many other medications, two cancer-pharmacology specialists suggest in a commentary in the July 16, 2007, issue of the Journal of Clinical Oncology. 


Potential new target for cancer found
bianjie submitted, created time 2 years 8 months (www.eurekalert.org)
By bypassing a well-known gene implicated in almost one-third of all cancers and instead focusing on the protein activated by the gene, Duke University Medical Center researchers believe they may have found a new target for anti-cancer drugs. 


Study: Some bone cancer drugs problematic
bianjie submitted, created time 2 years 8 months (www.sciencedaily.com)
U.S. scientists have determined the use of certain drugs to fight cancer-related bone problems might increase the risk of disease or infection. 


High blood pressure medication strategy proves effective in Hispanic women
bianjie submitted, created time 2 years 8 months (www.eurekalert.org)
Researchers studied 22,500 patients enrolled in the landmark International Verapamil SR-Trandolapril study, known as INVEST, and tracked a subgroup of 5,017 Hispanic and 4,710 non-Hispanic white women who were randomly assigned to a drug strategy containing either a sustained release form of the calcium antagonist verapamil or the beta-blocker atenolol. Hispanic women achieved greater blood pressure control and were half as likely as white women to suffer adverse outcomes. 