Articles with the keyword: 
Secret to Night Vision Found in DNA's Unconventional Architecture
sea-maid submitted, created time 10 months 3 weeks (www.sciencedaily.com)
Researchers have discovered an important element for making night vision possible in nocturnal mammals: the DNA within the photoreceptor rod cells, which is responsible for low light vision, is packaged in a very unconventional way. That special DNA architecture turns the rod cell nuclei themselves into tiny light-collecting lenses, millions of them in every nocturnal eye.
These results are reported in the April 17th issue of Cell. 
CSHL researchers explain process by which cells hide potentially dangerous DNA segments
piggy submitted, created time 11 months 1 week (www.eurekalert.org)
The DNA in the twenty-three pairs of chromosomes in each of the billions of cells of the human body is so tightly packed that it would measure six feet in length if stretched end to end. A genome of this size can squeeze into a cell's tiny nucleus because it is compressed into highly condensed chromatin fibers by proteins called histones.
Not all of the genome is condensed to an equal degree. A portion of it might well be called super-condensed; it forms a kind of chromatin called heterochromatin
Chemists Create Bipedal, Autonomous DNA Walker
sea-maid submitted, created time 11 months 2 weeks (www.sciencedaily.com)
Chemists at New York University and Harvard University have created a bipedal, autonomous DNA "walker" that can mimic a cell's transportation system. The device, which marks a step toward more complex synthetic molecular motor systems, is described in the most recent issue of the journal Science.
Special investigation: How my genome was hacked
sea-maid submitted, created time 11 months 2 weeks (www.newscientist.com)
INTIMATE secrets hidden in your DNA could be stolen without you even realizing. By taking a glass from which you have drunk, a "genome hacker" could obtain a comprehensive scan of your genome, revealing DNA variants that help determine your susceptibility to a wide range of diseases, from a common form of blindness to Alzheimer's disease.
DNA cages guide nanoparticle self-assembly
sea-maid submitted, created time 1 year 3 days (www.newscientist.com)
TRAPPING nanoparticles in cages made of DNA could finally allow them to self-assemble into transistors, metamaterials and even tiny robots. The technique should prevent the nanoparticles clumping together at random, one of the biggest problems with nanoscale self-assembly.
Researchers devise new way to explore DNA
piggy submitted, created time 1 year 1 week (www.eurekalert.org)
A team including researchers from the National Institutes of Health (NIH) has found a new way of detecting functional regions in the human genome. The novel approach involves looking at the three-dimensional shape of the genome's DNA instead of only reading the nucleotide sequence.
In a paper published in the early online edition of Science, a team led by Elliott Margulies, Ph.D., of the National Human Genome Research Institute (NHGRI), and Thomas Tullius, Ph.D., of Boston University, describes an innovative approach for detecting functional genomic regions
piggy submitted, created time 1 year 2 months (sciencenow.sciencemag.org)
Call it the genetic version of a double-entendre. Scientific dogma dictates that various three-letter combinations of our genetic sequence each "mean" exactly one thing--each codes for a particular amino acid, the building block of proteins. But a protozoan named Euplotes crassus appears to be more versatile: One of its three-letter combinations has two meanings, coding for two different amino acids. Although the find may seem trivial, it poses a major challenge to more than four decades of scientific thinking.
It's a long road from gene to protein
Biologists learn structure, mechanism of powerful "molecular motor" in virus
piggy submitted, created time 1 year 2 months (news.uns.purdue.edu)
Researchers have discovered the atomic structure of a powerful "molecular motor" that packages DNA into the head segment of some viruses during their assembly, an essential step in their ability to multiply and infect new host organisms.
The researchers, from Purdue University and The Catholic University of America, also have proposed a mechanism for how the motor works
Nanotubes Sniff Out Cancer Agents in Living Cells
piggy submitted, created time 1 year 3 months (www.sciencedaily.com)
MIT engineers have developed carbon nanotubes into sensors for cancer drugs and other DNA-damaging agents inside living cells.
The sensors, made of carbon nanotubes wrapped in DNA, can detect chemotherapy drugs such as cisplatin as well as environmental toxins and free radicals that damage DNA.
"We've made a sensor that can be placed in living cells, healthy or malignant, and actually detect several different classes of molecules that damage DNA," said Michael Strano, associate professor of chemical engineering and senior author of a paper on the work appearing in the Dec
Proteins that read DNA backwards
piggy submitted, created time 1 year 3 months (www.nature.com)
Some enzymes transcribe DNA in the "wrong" direction, creating puzzling RNAs.
Over the past decade, biologists have learned to credit RNA with more respect than it once garnered. Previously thought of simply as a chemical intermediate between DNA and protein, a host of RNA oddities that can switch genes off and on has revised that view.
Now, a suite of papers published in Science this week promises to add still more complexity by revealing several new classes of peculiar RNA molecules, many of which are created when proteins read DNA backwards
Memories may be stored on your DNA
sea-maid submitted, created time 1 year 3 months (www.newscientist.com)
REMEMBER your first kiss? Experiments in mice suggest that patterns of chemical "caps" on our DNA may be responsible for preserving such memories.
To remember a particular event, a specific sequence of neurons must fire at just the right time. For this to happen, neurons must be connected in a certain way by chemical junctions called synapses. But how they last over decades, given that proteins in the brain, including those that form synapses, are destroyed and replaced constantly, is a mystery
Misreading of Damaged DNA May Spur Tumor Formation
sea-maid submitted, created time 1 year 3 months (www.sciencedaily.com)
The DNA in our cells is constantly under assault from oxygen, the sun's radiation and environmental stresses. Most of the time, our cells can repair the damage before it gets copied into a permanent mutation that could lead to cancer.
Loulan Beauty upsets Chinese View of Colonization of Xinjiang
Darkfrog submitted, created time 1 year 4 months (www.nytimes.com)
In Xinjiang, a part of China that mainstream culture considers to be entirely Chinese, the discovery of over two hundred extremely well-preserved and marketly not Han Chinese mummies have called that assertion into question. Xinjiang borders Kazakh and Mongolia.
My take? Well DUH. Human beings migrate like crazy. Borders change. My ancestors moved from God-knows-where to Ireland, displacing the people who lived there earlier. Today we call their other descendants "Irish" and wouldn't think of calling them anything else
DNA: Too Much--or Too Little--Can Be a Bad Thing
piggy submitted, created time 1 year 4 months (sciencenow.sciencemag.org)
There's more variety to DNA than you might think: Deletions or additions of genetic material between individuals, called copy number variations (CNVs), are a common source of genetic diversity. Now, preliminary work reported here today at the American Society of Human Genetics meeting suggests that men who have more CNVs than average may be more likely to sire children with the eye cancer retinoblastoma
Biologists Discover Motor Protein That Rewinds DNA
piggy submitted, created time 1 year 4 months (www.sciencedaily.com)
ScienceDaily (Nov. 2, 2008) — Two biologists at the University of California, San Diego have discovered the first of a new class of cellular motor proteins that “rewind” sections of the double-stranded DNA molecule that become unwound, like the tangled ribbons from a cassette tape, in “bubbles” that prevent critical genes from being expressed.
“When your DNA gets stuck in the unwound position, your cells are in big trouble, and in humans, that ultimately leads to death” said Jim Kadonaga, a professor of biology at UCSD who headed the study
abuse@discover8.com
kavin
angelfish
jane2007
Sue Wu
DanyC
GenScript plasmid DNA preparation services offer endotoxin FREE and predominantly supercoiling plasmid DNA from 100 ug to 1000 mg start from $50.
www.genscript.com
Catalog Stable Cell Lines
GenScript offers a wide selection of GPCR stable cell lines optimized to various assay readouts such as calcium, chemiluminescence, GFP, and FRET.
www.genscript.com