Articles with the keyword:
10

Daughter cells share duties

sea-maid submitted, created time 4 years 10 months (www.jcb.org)

There’s no sibling rivalry during cell division. Goss and Toomre show that during cytokinesis both daughter cells pitch in to supply new membrane.

13

cytokinesis unveiled: forming the furrows

sea-maid submitted, created time 5 years 3 weeks (www.jcb.org)

This paper is about a monopolar HeLa system which is used to determine how the cytokinetic furrow is created. From the research,the author tells us that splitting mitotic cells in two is not the one-way signaling road it once seemed, based on evidence from Hu et al.

5

A novel role in cytokinesis reveals a housekeeping function for the unfolded protein response

DanyC submitted, created time 5 years 11 months (www.jcb.org)

“The unfolded protein response (UPR) pathway helps cells cope with endoplasmic reticulum (ER) stress by activating genes that increase the ER's functional capabilities. We have identified a novel role for the UPR pathway in facilitating budding yeast cytokinesis. Although other cell cycle events are unaffected by conditions that disrupt ER function, cytokinesis is sensitive to these conditions. Moreover, efficient cytokinesis requires the UPR pathway even during unstressed growth conditions. UPR-deficient cells are defective in cytokinesis, and cytokinesis mutants activate the UPR

6

Pombe Cdc15 homology (PCH) proteins: coordinators of membrane–cytoskeletal interactions

medal submitted, created time 6 years 1 month (www.sciencedirect.com)

"Cellular adhesion, motility, endocytosis, exocytosis and cytokinesis involve the coordinated reorganization of the cytoskeleton and of the plasma membrane. The ‘Pombe Cdc15 homology’ (PCH) family of adaptor proteins has recently been shown to coordinate the membrane and cytoskeletal dynamics involved in these processes by curving membranes, recruiting dynamin and controlling the architecture of the actin cytoskeleton. Mutations in PCH family members or proteins that interact with them are associated with autoinflammatory, neurological or neoplastic diseases

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