Articles with the keyword: 


Daily HIV/Aids Report Reviews Washington D.C.
sea-maid submitted, created time 11 months 2 weeks (allafrica.com)
This article talks about how the city of Washington D.C. has managed to reduce the spread of HIV within its limits. Washington D.C. has one of the highest HIV infection rates in the U.S. The article lauds needle exchange programs and a recent end to the Congressional ban on using public money to fund them, but insists that public awareness must be improved. 


Molecular farming becomes practical: One million doses of anti-HIV protein grown in plants
Darkfrog submitted, created time 11 months 2 weeks (www.nature.com)
1. It's a protein that interferes with HIV in human cell studies, probably by binding to the virus's surface. Unlike non-protein microbicides, it actually seems to work.
2. It was grown in plants. This means it would be cheap. Proteins of this kind are usually very expensive to mass-produce.
The genes coding for the protein were introduced into a type of tobacco plant called Nicotiana benthamiana using the tobacco mosaic virus. The protein itself is called griffithsin (GRFT), and is found in red algae 


AIDS Drug Slows Spread of Deadly Childhood Brain Cancer
sea-maid submitted, created time 11 months 2 weeks (news.yahoo.com)
A drug approved to combat AIDS may also help slow the spread of a deadly type of brain tumor that tends to attack children. 


Researchers progress toward AIDS vaccine
piggy submitted, created time 1 year 6 days (www.eurekalert.org)
Rutgers AIDS researchers Gail Ferstandig Arnold and Eddy Arnold may have turned a corner in their search for a HIV vaccine. In a paper just published in the Journal of Virology, the husband and wife duo and their colleagues report on their research progress.
With the support of the National Institutes of Health, the Arnolds and their team have been able to take a piece of HIV that is involved with helping the virus enter cells, put it on the surface of a common cold virus, and then immunize animals with it 


Old Strategy for Tackling HIV Makes a Comeback
piggy submitted, created time 1 year 2 weeks (sciencenow.sciencemag.org)
For twenty years, AIDS researchers have searched for a vaginal microbicide that can block HIV, but they have made little progress. One gel has shown hints of working in a large-scale human study, but the rest have failed or even caused harm. Now a new monkey study suggests that a microbicide containing a compound that many investigators would consider old-fashioned may have the power to thwart the AIDS virus 


Microbicide may prevent HIV from gaining a foothold in the body
Darkfrog submitted, created time 1 year 2 weeks (www.nature.com)
Glycerol monolaurate, a microbicide often used as an additive in foods and cosmetics, has been shown to protect female monkeys from contracting SIV, the simian equivalent of HIV. Ironically, it seems to work by suppressing the immune system.
During the early stages of HIV infection, the body musters an immune response to fight it off. Unfortunately for us, this immune response contains a significant does of CD4+ helper T-cells--the virus's favorite food. Suppress this immune response, and it may become harder for HIV to gain a foothold 


HIV Adapts to Escape Immune Response
piggy submitted, created time 1 year 2 weeks (main.uab.edu)
A new study out of the University of Alabama at Birmingham (UAB) and Oxford University in England describes the human immunodeficiency virus's ability to adapt and avoid the human immune system. It spells out at least fourteen different changes, called escape mutations, that help keep itself alive after interacting genetically with the immunity molecules that would normally attack it.
The human immunodeficiency virus (HIV) adapts so well to the body's defense system that any successful AIDS vaccine must keep pace with the ever-changing immunological profile of the virus 


HIV Is Evolving to Evade Human Immune Responses
sea-maid submitted, created time 1 year 2 weeks (www.sciencedaily.com)
HIV is evolving rapidly to escape the human immune system, an international study led by Oxford University has shown. The findings, published in Nature, demonstrate the challenge involved in developing a vaccine for HIV that keeps pace with the changing nature of the virus. 


Stem cell transplant wipes out HIV
sea-maid submitted, created time 1 year 1 month (www.nature.com)
A man may have been cured of both HIV and leukemia after receiving a stem-cell transplant from a donor who is genetically resistant to HIV. Two years down the line, the patient has no detectable HIV virus in his system, even though he has stopped his regimen of antiretroviral drugs.
The mechanics of the treatment were no different from any other leukemia bone marrow transplant, which took place in Germany 


Novel HIV-Fighting Method Finally Gels
piggy submitted, created time 1 year 1 month (sciencenow.sciencemag.org)
Trials of microbicide gels to protect women against HIV infection have a perfect record--not one of them has worked, and some were even harmful. But now a large international study has ended that curse, although the gel's benefits appear to be modest and require confirmation.
As reported here today at the 16th Conference on Retroviruses and Opportunistic Infections, the study showed that a microbicide called PRO 2000 reduced the risk of HIV infection by 30% 


Synthetic Molecules Prevent HIV Virus From Reproducing within the Body, Study Suggests
sea-maid submitted, created time 1 year 3 months (www.sciencedaily.com)
Evolving HIV viral strains and the adverse side effects associated with long-term exposure to current treatments propel scientists to continue exploring alternative HIV treatments. In a new study, a University of Missouri researcher has identified broad-spectrum aptamers. Aptamers are synthetic molecules that prevent the HIV virus from reproducing. In lab tests, aptamers known as RT5, RT6, RT47 and some variants of those were recently identified to be broad-spectrum, which would allow them to treat many subtypes of HIV-1. 


New Way Men Can Transmit HIV to Women
piggy submitted, created time 1 year 3 months (www.sciencedaily.com)
Researchers at Northwestern University have discovered a critical new way a man can transmit the HIV virus to a woman.
Scientists had long believed that the normal lining of the female vaginal tract was an effective barrier to invasion of the HIV virus during sexual intercourse. They thought the large HIV virus couldn't penetrate the tissue.
But new research from Northwestern University's Feinberg School of Medicine has shown for the first time that the HIV virus does indeed penetrate a woman's normal, healthy genital tissue to a depth were it can gain access to its immune cell targets. 


Antibody fights AIDS-like disease in monkeys
sea-maid submitted, created time 1 year 3 months (www.nature.com)
An antibody treatment has rejuvenated the immune systems of macaques infected with a virus called SIV, allowing the monkeys to fend off the symptoms of an AIDS-like disease for months. SIV is studied as a model for HIV infection in humans, and the therapy could be tested in clinical trials of HIV-infected patients as soon as next year, pending approval by regulators. 


HIV testing on the cheap! ...but no one's interested.
Darkfrog submitted, created time 1 year 3 months (www.nature.com)
The standard HIV test, such as a patient might receive in a hospital in New York or Paris, is generally too expensive for AIDS prevention organizations in Africa. However, new developments that could make HIV testing more feasible are not garnering enough interest from private investors.
These tests are not limited to determining who is infected and who isn't. For example, CD4 tests, which measure HIV-indicative changes in the patient's cell receptors, are used to tell how far the disease has progressed, which can help doctors give their patients the most effective drug regimens 


Discovery of Lentivirus in Lemur Could Shed Light on History of AIDS and HIV
piggy submitted, created time 1 year 3 months (www.sciencedaily.com)
The genome of a squirrel-sized, saucer-eyed lemur from Madagascar may help scientists understand how HIV-like viruses coevolved with primates, according to new research from the Stanford University School of Medicine. The discovery, to be published online on Dec. 1 in the Proceedings of the National Academy of Sciences, could provide insight into why non-human primates don't get AIDS and lead to treatments for humans.
Scientists have long believed that lentiviruses — the family of viruses that includes HIV — started infecting primates within the past million years 