Reconstitution of a microtubule plus-end tracking system in vitro

Sue Wu submitted, created time 5 years 6 months (www.nature.com)

The microtubule cytoskeleton is essential to cell morphogenesis. Growing microtubule plus ends have emerged as dynamic regulatory sites in which specialized proteins, called plus-end-binding proteins (+TIPs), bind and regulate the proper functioning of microtubules.

Keywords: calcium binding proteins Microtubules cytoskeleton microtubule-associated proteins